This form of breast cancer is often mistaken for skin conditions such as dermatitis or eczema. Paget disease of the breast also known as Paget disease of the nipple, or mammary Paget disease is a form of breast cancer that's present in about one percent of all breast cancer cases, according to the American Cancer Society. The disease starts in the breast ducts and spreads to the skin of the nipple, then to the areola dark circle around the nipple. Paget disease is frequently misdiagnosed at first, because its early symptoms can easily be confused with those of more common skin conditions affecting the nipple. This disease is not related to Paget's disease of the bone, which is a metabolic bone disease. While it's not known exactly what causes Paget disease of the breast, the following two theories are most widely believed to explain its onset:.
What is Paget's Disease of the Breast?
Paget's disease of the breast - Libre Pathology
Paget disease of the breast , which is also known as Paget disease of the nipple , has traditionally been described as a form of breast malignancy characterized by infiltration of the nipple epidermis by malignant cells. Although most cases have underlying focus or foci of in situ or invasive carcinomas, some cases of Paget disease are confined to the skin of the nipple-areola without underlying neoplastic foci. The average age at diagnosis is around the 6 th decade years. Eczematous appearing changes of the nipple include reddening, scaling, hyperkeratosis, and crusting of the nipple surface. In most cases of Paget of the breast, there are malignant ductal cells that extend to the nipple surface through the terminal lactiferous ducts.
pictures of paget s disease of the areola
Paget disease of the breast also known as Paget disease of the nipple and mammary Paget disease is a rare type of cancer involving the skin of the nipple and, usually, the darker circle of skin around it, which is called the areola. Most people with Paget disease of the breast also have one or more tumors inside the same breast. These breast tumors are either ductal carcinoma in situ or invasive breast cancer 1 — 3.
Written by: Jean Watkins Published: 21 October For more on this subject Click here. Better results are not only due to the possibilities of more effective treatment but also the fact that the condition is being recognized at an earlier stage.